Aomics GmbH

Antibody optimisation
Antibody optimisation

By using our bioinformatics expertise we optimise antibodies, so that researchers can design antibodies that are more effective in targeting specific antigens, have improved pharmacokinetic properties, and are less likely to cause adverse effects in patients. This approach can help to accelerate the development of new and effective immunotherapies for a range of diseases, including cancer and autoimmune disorders.

We develop AI-based computational solutions for modifying and optimising the properties of antibodies, such as their binding affinity, specificity, and stability, for future fherapeutics
Immune modulators discovery
Immune modulators discovery

Our highly trained interdisciplinary team use state-of-the-art AI technologies to identify potential targets, pathways, and mechanisms of action of small molecules, which can help to accelerate the development of new and effective immunotherapies for a range of diseases, including cancer and autoimmune disorders.

We develop AI-based cheminformatics approaches for analysing massive compound libraries for immune modulator discovery
drug discovery platform
Artificial Intelligence (AI)-driven full stack drug discovery platform

Our highly trained interdisciplinary team use state-of-the-art AI technologies for developing novel approaches for Hit-to-lead identification and optimisation for an accelerated drug development workflow

We develop AI-based muti-omics and cheminformatics approaches for finding novel drug targets and evaluate their target disease efficacy
Clinical Biostatisticians
Collaborate with us for analysing clinical data and to have biostatistics consultation to get valuable insights for your clinical projects

Extremely committed team of biostatisticians, statistical programmers and AI engineers who help to deliver faster and meaningful information from your clinical studies

Clinical data management and Data analyses
Big-data for precision medicine
Big Biological/Healthcare Data Analytics for precision medicine
High quality data analytic services

Our team of healthcare data engineers help in structuring and analysing big data to develop precision treatment solutions

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Who we are?

Aomics GmbH is a deep-tech healthcare startup based in Europe, with its headquarters located in Frankfurt, Germany. Our focus is on utilising big biological data, deep learning, AI, and blockchain technologies to develop Immuno-Oncology and Immuno-Informatics Solutions. 

Our company has created a personalised immuno-oncology tool called Onco-Cure. Using patient-derived tumour microenvironment (TME) data, the Onco-Cure analytical dashboard predicts specific immune biomarkers for each patient and enables oncologists to select and plan the best targeted therapies. Our goal with Onco-Cure is to provide the most insightful, approved, and personalised therapy options to oncologists within a 48-hour timeframe.

Compounds in Pipeline

Program

Monoclonal antibody

Monoclonal antibody

Small molecule

Small molecule

Discovery/Research

Preclinical

Clinical PoC Trials

Clinical Trial
Phase-I

Clinical Trial
Phase-II

Clinical Trial
Phase-III

NDA Filed
(FDA filing)

AOM-201901
AOM-202001
AOM-Rare-202101
AOM-Covid19-202002

Technologies under development

Phase-1

Conceptualization

Phase-2

Proof of Concept

Phase-3

Testing & Validation

Phase-4

Launch & Marketing

Phase-5

Scaling & Establishing

Onco-Cure
Immuno-Oncology data analysis pipeline
MULTIOMICS-ImmunoAI
Multi-omics based AI pipeline

Single-Cell Analysis for understanding Spatial Heterogeneity

Single-cell analysis is a valuable tool for understanding the spatial heterogeneity of the tumor microenvironment (TME). The TME is a complex and dynamic ecosystem composed of cancer cells, immune cells, stromal cells, and extracellular matrix components that interact with each other and shape the tumor's growth and progression. Single-cell analysis techniques, such as single-cell RNA sequencing (scRNA-seq) and imaging mass cytometry, can be used to analyze the gene expression and protein levels of individual cells within the TME. These techniques enable the identification of different cell types, such as tumor-infiltrating immune cells, cancer-associated fibroblasts, and endothelial cells, and can reveal the cellular heterogeneity within the TME.

Single cell sequencing for studying the immune system

Single-cell sequencing is a powerful tool for studying the immune system at the single-cell level. The immune system is composed of diverse cell types, including T cells, B cells, natural killer cells, dendritic cells, and macrophages, which work together to defend the body against pathogens and other threats. Single-cell sequencing techniques, such as single-cell RNA sequencing (scRNA-seq), can be used to analyze the gene expression of individual immune cells. This enables the identification of different immune cell types, as well as the identification of subsets and states within each cell type. For example, scRNA-seq can reveal the different types of T cells, such as CD4+ helper T cells and CD8+ cytotoxic T cells, and the different subsets of these cell types, such as memory T cells and regulatory T cells.

Artificial intelligence & Machine Learning for Immuno-informatics

Artificial intelligence (AI) and machine learning (ML) techniques are increasingly being used in immuno-informatics to analyze and interpret large amounts of data generated from high-throughput experiments. Immuno-informatics involves the application of computational and informatics methods to study the immune system, including the analysis of immune responses, vaccine design, and immunotherapy development. AI and ML techniques can be used to analyze high-dimensional datasets generated from techniques such as single-cell sequencing, mass spectrometry, and flow cytometry. These techniques can identify complex patterns and relationships between variables in the data that may be difficult or impossible to detect through manual analysis.

How we use Multi-omics data for Immuno target identification?

Multi-omics data integration is a powerful approach for identifying potential targets for immunotherapy development. Multi-omics data refers to the integration of multiple types of molecular data, such as genomics, transcriptomics, proteomics, and metabolomics, to provide a more comprehensive view of the molecular mechanisms underlying a disease or biological process. In the context of immuno target identification, multi-omics data integration can be used to identify potential targets for immunotherapy development. For example, by integrating genomics and transcriptomics data from patient samples, researchers can identify genes that are differentially expressed in tumor cells compared to normal cells. These differentially expressed genes may represent potential targets for immunotherapy development.

"AI empowered immuno-oncology solutions "

The recent advancements in multi-omics techniques, immunology, cancer biology, and computational algorithms have provided a deeper understanding of the molecular basis of cancer with increased precision. This has streamlined the oncological therapy process and improved the identification of immune biomarkers for immunotherapy. Aomics is dedicated to creating cutting-edge AI-based solutions for analyzing multi-omics healthcare/clinical data, with the goal of discovering new immuno-oncology solutions and identifying novel immune biomarkers. Our personalized immuno-oncology technologies allow oncologists to provide individualized treatments to their patients and advance our understanding of how a patient's own immune system can fight cancer.

Who We Are

We are a German based company, specialized in the area of drug discovery and drug target identification. By leveraging state-of-the-art artificial intelligence, multi-omics and cheminformatic techniques, we efficiently reduce the time and cost of the drug development process to several folds.

Our Mission

Make the best use of the state-of-the-art digital technologies, scientific knowledge and resources to accelerate the effective development of new diagnostic techniques and therapeutics for global health

Our Vision

“To develop highly efficient and effective diagnostic and therapeutic techniques for a healthy future

Our Values

Our Role

“To serve the patients who are unfortunately suffering with diseases with unmet medical needs by accelerating the development of highly efficient and effective diagnostic and therapeutic techniques

Our key priority

“Our key priority is to ensure that everyone has access to safe, affordable, fast and efficient solutions to the healthcare problems, especially for the disease areas with huge unmet medical needs”

What We Do

Would you like to start a project with us?

Reach out on the given number or write us an email for further queries regarding project requirements